Home News Medical 8 Biotechs With Coronavirus Vaccines In Development

8 Biotechs With Coronavirus Vaccines In Development

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As the COVID-19 pandemic rolls on, there are several companies racing to develop a vaccine. Although some countries have started to flatten the curve, with infection rates and deaths caused by the virus dropping, it will likely still be a significant issue globally for some time. The WHO says that there are around 35 vaccines currently in development. Below you can find some of the top biotech firms developing coronavirus vaccines.

Inovio Pharmaceutical Inc

Inovio Pharmaceutical Inc is developing a DNA plasmid vaccine. They are being funded by a number of agencies for developing INO-4800 and an intradermal vaccine delivery device. The firm is on track to begin mid-stage clinical testing by this summer. They want to make one million vaccines by the end of 2020.

Applied DNA Sciences Inc and Takis Biotech

This company is developing a linear DNA vaccine. Applied DNA Sciences has said that the results from the DNA testing for their vaccine are “beyond expectations.” They will be beginning dose-responsive trials and say they have begun discussions with third parties for distribution, compliance, and marketing.

Johnson & Johnson’s and Janssen Unit

The non-replicating viral vector in development by J&J is being developed quickly. As well as partnering with Janssen Pharmaceutical Companies, they have also joined with the U.S. Biomedical Advanced Research and Development Authority. The J&J CEO, Alex Gorsky, says that their vaccine could be ready for testing in September.

Altimmune Inc

Altimmune is also developing a non-replicating viral vector vaccine. They aim to produce an intranasal vaccine and will be running preclinical trials of their product, AdCOVID, at the University of Alabama at Birmingham. Their goal is to begin phase I human trials in Q3 2020.

Novavax, Inc.

The nanoparticle vaccine in development by Novavax is set to begin human clinical trials this month. They have been awarded funding from CEPI (Coalition for Epidemic Preparedness Innovations), receiving the largest amount even given at $384 million. Their phase I research begins in Australia in May, before moving to phase II in multiple countries.

Moderna Inc

The Moderna Inc COVID vaccine candidate has been fast-tracked by the FDA. They are currently awaiting the results from their first phase study and are preparing for their second and third phase clinical trials. The Phase II study will look at the safety, reactogenicity, and immunogenicity of the mRNA vaccine.

Vaxart Inc

Vaxart Inc is developing an oral vaccine, for which they recently announced positive preclinical data. They began preclinical studies early, in January, based on their existing oral vaccines platform. The company has entered a development agreement with Emergent Biosolutions Inc to prepare for cGMP production of an oral COVID-19 vaccine.

BioNTech SE

BioNTech is working together with Pfizer to develop an mRNA vaccine. They are carrying out a global Phase I/II clinical trial that has been initiated in Germany and is beginning in the U.S. Both companies are making use of their facilities to manufacture and supply the vaccine.

Each of these biotech companies should be watched closely to observe the progress of their vaccine development.

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